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NeuroNova 1

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Drug Profile

NeuroNova 1

Alternative Names: CLD-101; NeuroNova-1; NNV-1

Latest Information Update: 07 Nov 2024

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At a glance

  • Originator Northwestern University
  • Developer Calidi Biotherapeutics; City of Hope National Medical Center; Northwestern University
  • Class Antineoplastics; Gene therapies; Immunotherapies; Oncolytic viruses; Stem cell therapies
  • Mechanism of Action Cell death stimulants; Immunologic cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Glioma
  • Preclinical Ovarian cancer

Most Recent Events

  • 30 Sep 2024 Calidi Biotherapeutics plans phase Ib/II clinical trial in Glioma (First-line therapy) in 1Q of 2025 in US (Intracerebral)
  • 30 Sep 2024 US FDA clears Investigational new drug (IND) application for CLD 101 for phase Ib/II clinical trial in Glioma
  • 20 Mar 2024 neuroNova 1 is still in preclinical trials for Ovarian canecr in USA

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