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ISB 1442

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Drug Profile

ISB 1442

Alternative Names: CD38 x CD47 biparatopic bispecific antibody; ISB-1442

Latest Information Update: 02 Feb 2024

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At a glance

  • Originator Ichnos Sciences
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Multiple myeloma
  • Preclinical Haematological malignancies

Most Recent Events

  • 30 Jan 2024 Glenmark and Ichnos enters into an alliance 'Ichnos Glenmark Innovation' to accelerate drug discovery in cancer treatment
  • 09 Dec 2023 Adverse events data, pharmacokinetics and pharmacodynamics data from a phase I/II trial for multiple myeloma presented at the 65th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2023)
  • 22 Mar 2023 ISB 1442 receives Orphan Drug status for Multiple myeloma (Second-line therapy or greater) in USA

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