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LTP 001

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Drug Profile

LTP 001

Alternative Names: LTP-001

Latest Information Update: 18 Jun 2024

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At a glance

  • Originator Novartis
  • Class Antifibrotics
  • Mechanism of Action SMURF1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Idiopathic pulmonary fibrosis; Pulmonary arterial hypertension

Most Recent Events

  • 14 May 2024 Novartis completes a phase II trial in Pulmonary arterial hypertension in Germany, Argentina, Netherlands, Poland, Spain, United Kingdom and USA (PO) (NCT05764265) (EudraCT2022-002007-38)
  • 25 Apr 2024 Novartis terminates a phase II trial in Pulmonary arterial hypertension in Germany, Argentina, Netherlands, Poland, Spain, United Kingdom and USA (PO) (NCT05135000) (EudraCT2021-000670-28)
  • 27 Mar 2023 Phase-II clinical trials in Pulmonary arterial hypertension in USA, Argentina, United Kingdom, Poland, Netherlands, Germany (PO) (NCT05764265) (EudraCT2022-002007-38)

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