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BGB 16673

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Drug Profile

BGB 16673

Alternative Names: BGB-1663; BGB-16673; Chimeric Degradation Activating Compound (CDAC) targeting BTK - BeiGene

Latest Information Update: 15 May 2024

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At a glance

  • Originator BeiGene
  • Class Antineoplastics
  • Mechanism of Action Agammaglobulinaemia tyrosine kinase degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mantle-cell lymphoma
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II B-cell lymphoma; Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma
  • Phase I Mantle-cell lymphoma; Waldenstrom's macroglobulinaemia

Most Recent Events

  • 08 May 2024 BeiGene plans a phase III trial for Chronic lymphocytic leukemia by the end of 2024
  • 26 Feb 2024 BGB 16673 receives Orphan Drug status for Mantle-cell lymphoma (Second-line therapy or greater) in USA
  • 26 Feb 2024 BGB 16673 receives Fast Track designation for Mantle cell lymphoma (Second-line therapy or greater) in USA before February 2024
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