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Research programme: gap junction protein mediated hearing loss gene therapies - Akouos

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Drug Profile

Research programme: gap junction protein mediated hearing loss gene therapies - Akouos

Alternative Names: GJB2 gene therapies - Akouos; Hearing loss gene therapies - Akouos

Latest Information Update: 28 Sep 2025

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At a glance

  • Originator Akouos
  • Class Ear disorder therapies; Gene therapies
  • Mechanism of Action Gene transference; GJB2 protein replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Research Hearing loss

Most Recent Events

  • 28 Sep 2025 No recent reports of development identified for research development in Hearing loss in USA (Parenteral)
  • 31 Oct 2024 Gap junction protein mediated hearing loss gene therapies is still in early research phase for Hearing loss in USA (Parenteral) (Akouos pipeline, October 2024)
  • 01 Dec 2022 Akouos has been acquired by Eli Lilly and Company

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