XRD 0394
Alternative Names: XRD-0394Latest Information Update: 24 Feb 2025
At a glance
- Originator XRad Therapeutics
- Class Antineoplastics; Radioprotectives; Small molecules
- Mechanism of Action Ataxia telangiectasia mutated protein inhibitors; DNA-activated protein kinase inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Solid tumours
Most Recent Events
- 24 Feb 2025 Phase-I development is ongoing in USA (NCT05002140)
- 20 Feb 2025 XRad Therapeutics and NYU Langone Health plan a phase 0 (an early phase I) trial for Glioma (Combination therapy, Recurrent, Late-stage disease, First-line therapy) in USA (PO), in April 2025 (NCT06829173)
- 05 Apr 2024 Adverse events and pharmacokinetic data from a phase I trial in Solid tumours presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)