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AN 4005

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Drug Profile

AN 4005

Alternative Names: AN-4005

Latest Information Update: 03 Feb 2022

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At a glance

  • Originator Adlai Nortye
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Programmed cell death-1 ligand-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Lymphoma; Solid tumours

Most Recent Events

  • 27 Jan 2022 Adlai Nortye enters into licensing agreement with Xiamen Biotime Biotechnology for the development, manufacturing and commercialization of AN 4005 in China
  • 27 Sep 2021 Phase-I clinical trials in Lymphoma (Second-line therapy or greater, Late-stage disease) in USA (PO) (NCT04999384)
  • 27 Sep 2021 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Inoperable/Unresectable) in USA (PO) (NCT04999384)

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