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NGM 831

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Drug Profile

NGM 831

Alternative Names: NGM-831

Latest Information Update: 22 Aug 2025

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At a glance

  • Originator NGM Biopharmaceuticals
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; LILRB4 protein inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 22 Aug 2025 NGM 831 is still in phase I development in Solid-tumours (Combination therapy, Late-stage disease, Metastatic disease) in USA (IV) (NCT05215574)
  • 22 Aug 2025 NGM 831 is still in phase I development in Solid-tumours (Monotherapy, Late-stage disease, Metastatic disease) in USA (IV) (NCT05215574)
  • 28 Mar 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Metastatic disease) in USA (IV)

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