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ARR 002

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Drug Profile

ARR 002

Alternative Names: ARR-002; AV-P138-ADC

Latest Information Update: 20 Aug 2026

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At a glance

  • Originator Aarvik Therapeutics
  • Class Antibodies; Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates; Immunotoxins
  • Mechanism of Action Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Endometrial cancer; Ovarian cancer

Most Recent Events

  • 23 Jul 2026 Phase-I clinical trials in Endometrial cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (Parenteral) (NCT07755436)
  • 23 Jul 2026 Phase-I clinical trials in Ovarian cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (Parenteral) (NCT07755436)
  • 07 May 2026 Arrivent Biopharma plans to initiate a phase I trial in Ovarian cancer and Endometrial cancer in USA (Parenteral), in the second half of 2026

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