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TOP N53

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Drug Profile

TOP N53

Alternative Names: TOP-N-53

Latest Information Update: 23 Sep 2025

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At a glance

  • Originator Topadur Pharma
  • Class Antiulcers; Foot disorder therapies; Skin disorder therapies; Small molecules
  • Mechanism of Action Nitric oxide donors; Type 5 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Skin ulcer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Skin ulcer
  • Phase I Diabetic foot ulcer

Most Recent Events

  • 09 Sep 2025 TOP N53 receives Orphan Drug status for Skin ulcer in USA
  • 28 Nov 2023 Phase-I clinical development in Diabetic foot ulcer (In volunteers) is ongoing in Switzerland (SC) (Topadur Pharma pipeline, November 2023)
  • 28 Nov 2023 Phase-I clinical development in Skin ulcer (In volunteers) is ongoing in Switzerland (SC) (Topadur Pharma pipeline, November 2023)

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