Drug Profile

THB 001

Alternative Names: THB-001

Latest Information Update: 16 Sep 2026

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At a glance

Originator Third Harmonic Bio.
Developer Third Harmonic Bio
Class Antiasthmatics; Skin disorder therapies; Small molecules
Mechanism of Action Proto-oncogene protein c-kit inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Discontinued Asthma; Cold Urticaria

Most Recent Events

15 May 2026 Pharmacodynamics data from a preclinical study in Asthma presented at the 122nd International Conference of the American Thoracic Society (ATS-2026)
08 Aug 2024 Discontinued - Phase-I for Cold urticaria (In the elderly, In adults) in Germany (PO)
08 Aug 2024 Discontinued - Phase-I for Cold urticaria (In the elderly, In adults) in Netherlands (PO)

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