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KTM 101

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Drug Profile

KTM 101

Alternative Names: ERAS-801; KTM-101

Latest Information Update: 28 May 2026

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At a glance

  • Originator The Regents of the University of California
  • Developer Katmai Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action ErbB receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioblastoma
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Glioblastoma
  • Preclinical CNS cancer

Most Recent Events

  • 28 May 2026 No recent reports of development identified for phase-I development in Glioblastoma(In the elderly, Recurrent, Second-line therapy or greater, In adults) in USA (PO)
  • 22 May 2026 Katmai Pharmaceuticals plans a phase II/III trial Primary brain cancers (Katmai Pharmaceuticals website, May 2026)
  • 30 Jul 2025 Jonsson Comprehensive Cancer Center plans a phase Ib trial for Glioblastoma (Recurrent, Late stage disease, Second line therapy or greater) in USA (PO) (NCT07089641)

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