Drug Profile

Research programme: ULK small molecule inhibitors - Erasca

Alternative Names: ERAS-5; ERAS-5 programme - Erasca

Latest Information Update: 28 Oct 2025

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At a glance

Originator LifeArc
Developer Erasca
Class Antineoplastics; Small molecules
Mechanism of Action Autophagy-related protein-1 homolog inhibitors; Ulk2 protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

No development reported Solid tumours

Most Recent Events

28 Oct 2025 No recent reports of development identified for research development in Solid-tumours in USA
31 Dec 2022 Erasca has patent pending for ULK1 and ULK2 inhibitors, their preparation and method of use
31 Dec 2022 Erasca has worldwide protection for ULK1 and ULK2 inhibitors, their preparation and method of use

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