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NMS 03597812

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Drug Profile

NMS 03597812

Alternative Names: NMS-03597812; NMS-812

Latest Information Update: 28 Oct 2025

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At a glance

  • Originator Nerviano Medical Sciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action EIF-2 kinase inhibitors; EIF2AK4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Multiple myeloma

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Multiple myeloma

Most Recent Events

  • 28 Oct 2025 No recent reports of development identified for phase-I development in Multiple-myeloma(Combination therapy, Second-line therapy or greater) in USA (PO)
  • 28 Oct 2025 No recent reports of development identified for phase-I development in Multiple-myeloma(Monotherapy, Second-line therapy or greater) in USA (PO)
  • 28 Aug 2024 Phase-I clinical trials in Acute myeloid leukaemia (Second-line therapy or greater, Monotherapy) in USA (PO) (NCT06549790)

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