Psoralen based cancer therapeutics - Immunolight
Alternative Names: X-PACT (X-ray Psoralen Activated Cancer Treatment) system; X-PACT system; X-ray Psoralen Activated Cancer Treatment systemLatest Information Update: 26 Feb 2025
At a glance
- Originator Immunolight
- Class Antineoplastics; Psoralens; Small molecules
- Mechanism of Action DNA cross linking agents; Photosensitisers
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Solid tumours
Most Recent Events
- 20 Feb 2025 Phase-I development is ongoing in USA (Intratumoural) (NCT06836648)
- 20 Feb 2025 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins and Immunolight initiate an expanded access trial of X-PACT for Prostate cancer (In adults, In the elderly, Second-line therapy or greater) in USA (Intratumoural, Injection), prior to February 2025 (NCT06836648)
- 05 Apr 2024 Pharmacokinetics data from a preclinical trial in Solid tumors presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)