Drug Profile

BMS 986419

Alternative Names: BMS-986419; eIF2b activator - Bristol-Myers Squibb; EOAI-4018683; EVT-8683

Latest Information Update: 28 Feb 2025

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At a glance

Originator Evotec SE
Developer Bristol-Myers Squibb; Evotec SE
Class Small molecules
Mechanism of Action Eukaryotic initiation factor 2b stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Highest Development Phases

Phase I Neurodegenerative disorders

Most Recent Events

28 Feb 2025 No recent reports of development identified for phase-I development in Neurodegenerative-disorders in Germany (PO, Tablet)
27 Feb 2025 Bristol-Myers Squibb initiates phase-I safety and pharmacokinetics trial (In volunteers) in USA (PO) (NCT06846866)
26 Feb 2025 Bristol Myers Squibb plans a phase I trial in Healthy volunteers (PO) (NCT06846866)

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