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ABBV 400

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Drug Profile

ABBV 400

Alternative Names: ABBV-400

Latest Information Update: 03 Oct 2024

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At a glance

  • Originator AbbVie
  • Class Antibodies; Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Colorectal cancer
  • Phase I Gastric cancer; Non-small cell lung cancer; Oesophageal cancer; Solid tumours

Most Recent Events

  • 26 Sep 2024 AbbVie plans a phase III trial for Colorectal cancer (Combination therapy, Metastatic disease, Second-line therapy or greater) (IV, Infusion) (NCT06614192)
  • 21 Jun 2024 AbbVie plans a phase I/II trial in Colorectal cancer and Solid tumour (Late-stage disease, Metastatic disease, Inoperable/Unresectable) in China (IV, Infusion) (NCT06464692)
  • 31 May 2024 Updated adverse events data from a phase I trial in Solid tumours presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)

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