ALXN 2420
Alternative Names: ALXN-2420; AZP-3813Latest Information Update: 11 May 2026
At a glance
- Originator PeptiDream
- Developer Amolyt Pharma
- Class Bicyclic peptides; Macrocyclic compounds; Peptides
- Mechanism of Action Somatotropin receptor antagonists
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Acromegaly
Most Recent Events
- 31 Mar 2026 Discontinued - Phase-II for Acromegaly (Combination therapy) in Lithuania, Romania, Italy, Brazil, Argentina, China, Denmark, Hungary, Poland, Netherlands, USA (SC), due to strategic reasons (AstraZeneca pipeline, May 2026)
- 31 Mar 2026 Alexion Pharmaceuticals terminates the phase-II ASTERIA trial for Acromegaly (Combination therapy) in Lithuania, Romania, Italy, Brazil, Argentina, China, Denmark, Hungary, Poland, Netherlands, USA (SC), due to strategic reasons (AstraZeneca pipeline, May 2026) (NCT07037420)
- 28 Oct 2025 Phase-II clinical trials in Acromegaly (Combination therapy) in USA, Argentina, Italy, Lithuania, Romania (SC) (NCT07037420)