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ALXN 2420

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Drug Profile

ALXN 2420

Alternative Names: ALXN-2420; AZP-3813

Latest Information Update: 27 Nov 2025

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At a glance

  • Originator PeptiDream
  • Developer Amolyt Pharma
  • Class Bicyclic peptides; Macrocyclic compounds; Peptides
  • Mechanism of Action Somatotropin receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acromegaly

Most Recent Events

  • 28 Oct 2025 Phase-II clinical trials in Acromegaly (Combination therapy) in USA, Argentina, Italy, Lithuania, Romania (SC) (NCT07037420)
  • 24 Sep 2025 Alexion Pharmaceuticals plans a phase II ASTERIA trial for Acromegaly (Combination therapy, In adults, In the elderly) in Argentina, Brazil, China, Denmark, Hungary, Italy, Lithuania, the Netherlands, Poland, Romania, United States (SC) (NCT07037420)
  • 15 Jul 2024 Amolyt Pharma has been acquired by AstraZeneca

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