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ALXN 2420

Drug Profile

ALXN 2420

Alternative Names: ALXN-2420; AZP-3813

Latest Information Update: 11 May 2026

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At a glance

  • Originator PeptiDream
  • Developer Amolyt Pharma
  • Class Bicyclic peptides; Macrocyclic compounds; Peptides
  • Mechanism of Action Somatotropin receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acromegaly

Most Recent Events

  • 31 Mar 2026 Discontinued - Phase-II for Acromegaly (Combination therapy) in Lithuania, Romania, Italy, Brazil, Argentina, China, Denmark, Hungary, Poland, Netherlands, USA (SC), due to strategic reasons (AstraZeneca pipeline, May 2026)
  • 31 Mar 2026 Alexion Pharmaceuticals terminates the phase-II ASTERIA trial for Acromegaly (Combination therapy) in Lithuania, Romania, Italy, Brazil, Argentina, China, Denmark, Hungary, Poland, Netherlands, USA (SC), due to strategic reasons (AstraZeneca pipeline, May 2026) (NCT07037420)
  • 28 Oct 2025 Phase-II clinical trials in Acromegaly (Combination therapy) in USA, Argentina, Italy, Lithuania, Romania (SC) (NCT07037420)

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