Drug Profile

EVO 390

Alternative Names: EVO-390; ROR gamma t modulator - Evommune; RORγt modulator - Evommune

Latest Information Update: 28 Oct 2025

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At a glance

Originator Dermira
Developer Evommune
Class Antipsoriatics; Small molecules
Mechanism of Action Nuclear receptor subfamily 1 group F member 3 modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes - Psoriasis

28 Oct 2025 No recent reports of development identified for preclinical development in Psoriasis in USA
15 Sep 2021 ROR gamma t modulator - Evommune is available for licensing as of 15 Sep 2021. https://www.evommune.com/ (Evommune website, September 2021)
09 Sep 2021 Preclinical trials in Psoriasis in USA (unspecified route) before September 2021 (Evommune pipeline, September 2021)

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