Drug Profile

PBGENE HBV

Alternative Names: PBGENE-HBV

Latest Information Update: 08 Dec 2025

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At a glance

Originator Precision Biosciences
Class Antivirals; Endoribonucleases; Gene therapies; RNA
Mechanism of Action Gene modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No
Available For Licensing Yes

Highest Development Phases

Phase I Hepatitis B

Most Recent Events

28 Nov 2025 Precision BioSciences plans a observational LTFU trial for Chronic HBV infection in unknown location (NCT07254208)
11 Nov 2025 Efficacy data from a phase I trial in Hepatitis B released by Precision Biosciences
14 Oct 2025 Medicines and Healthcare products Regulatory Agency approves IND application for PBGENE HBV for Phase-I ELIMINATE-B trial in United Kingdom before October 2025

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