Drug Profile

ATRN 119

Alternative Names: ATRN-119

Latest Information Update: 16 Feb 2026

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At a glance

Originator Atrin Pharmaceuticals
Class Antineoplastics; Macrocyclic compounds; Small molecules
Mechanism of Action ATR protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I/II Solid tumours

Most Recent Events

12 Feb 2026 Aprea Therapeutics has patent protection for ATR inhibitor in USA, Japan and other international jurisdictions
12 Feb 2026 Aprea Therapeutics has patents pending for ATR inhibitor in USA and other international jurisdictions
22 Oct 2025 Adverse events and pharmacokinetics data from a phase I/II trial in Solid tumour presented at International Conference on Molecular Targets and Cancer Therapeutics 2025 (AACR-NCI-EORTC-2025)

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