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ATRN 119

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Drug Profile

ATRN 119

Alternative Names: ATRN-119

Latest Information Update: 10 Dec 2025

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At a glance

  • Originator Atrin Pharmaceuticals
  • Class Antineoplastics; Macrocyclic compounds; Small molecules
  • Mechanism of Action ATR protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 22 Oct 2025 Adverse events and pharmacokinetics data from a phase I/II trial in Solid tumour presented at International Conference on Molecular Targets and Cancer Therapeutics 2025 (AACR-NCI-EORTC-2025)
  • 15 Oct 2025 Updated efficacy, adverse events and pharmacokinetics data from a phase I/II trial in Solid tumour released by Aprea Therapeutics
  • 15 Oct 2025 Aprea Therapeutics pause further enrollment in both once daily and twice daily monotherapy dosing arms of phase I/IIa ABOYA-119 trial in Solid tumours in USA

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