Drug Profile

ATRN 119

Alternative Names: ATRN-119

Latest Information Update: 28 May 2025

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At a glance

Originator Atrin Pharmaceuticals
Class Antineoplastics; Macrocyclic compounds; Small molecules
Mechanism of Action ATR protein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I/II Solid tumours

Most Recent Events

14 May 2025 Efficacy data from a phase I/II trial in Solid tumour released by Aprea Therapeutics
07 Nov 2024 Updated adverse events data from a phase I/II trial in Solid tumour released by Atrin Pharmaceuticals
23 Oct 2024 Updated adverse events data from a phase I/II trial in Solid tumour presented at the 36^th EORTC-NCI-AACR Symposium on molecular targets and cancer therapeutics (EORTC-NCI-AACR-2024)

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