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PM 1032

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Drug Profile

PM 1032

Alternative Names: anti-CLDN18.2 x 4-1BB biAb; CLDN18.2 x 4-1BB biAb; PM-1032

Latest Information Update: 11 Jul 2024

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At a glance

  • Originator Biotheus
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD137 antigen antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 31 May 2024 Safety, efficacy and pharmacokinetics data from a phase I/II trial in Solid tumours presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 31 May 2024 Biotheus plans a clinical trial in Solid tumours (Monotherapy, Combination therapy)
  • 08 Jul 2022 Phase-I/II clinical trials in Solid tumours (Late-stage disease, First-line therapy) in China (IV) (NCT05839106)

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