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Zeleciment Rostudirsen - Dyne Therapeutics

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Drug Profile

Zeleciment Rostudirsen - Dyne Therapeutics

Alternative Names: DYNE-251; z-rostudirsen

Latest Information Update: 12 Dec 2025

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At a glance

  • Originator Dyne Therapeutics
  • Class Antibodies; Antisense oligonucleotides; Drug conjugates; Immunoconjugates
  • Mechanism of Action Dystrophin expression stimulants; Gene silencing
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Duchenne muscular dystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Duchenne muscular dystrophy

Most Recent Events

  • 08 Dec 2025 Efficacy and adverse events data from phase I/II DELIVER trials in Duchenne muscular dystrophy released by Dyne Therapeutics
  • 08 Dec 2025 Dyne plans a global phase III clinical trial for Duchenne muscular dystrophy in quarter two of 2026 to support global approvals
  • 06 Nov 2025 Dyne Therapeutics announces intention to launch DYNE 251 for Duchenne muscular dystrophy in Q1 2027

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