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TolaSure topical gel - BioMendics

Drug Profile

TolaSure topical gel - BioMendics

Alternative Names: BM-3103; TolaSure; TolaSure topical gel

Latest Information Update: 02 Sep 2025

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At a glance

  • Originator BioMendics
  • Class Alkynes; Anisoles; Anti-infectives; Anti-inflammatories; Antibacterials; Antifungals; Antivirals; Phenols; Small molecules
  • Mechanism of Action Bacterial biofilm inhibitors; Bacterial growth inhibitors; Intermediate filament protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Epidermolysis bullosa
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Epidermolysis bullosa; Wounds
  • Preclinical Bacterial infections; Burns; Dermatitis; Ichthyosis; Methicillin-resistant Staphylococcus aureus infections; Mycoses; Psoriasis; Scleroderma; Skin ulcer

Most Recent Events

  • 02 Sep 2025 Chemical structure information added.
  • 07 Aug 2025 Adverse event and efficacy data from a phase I trial in Epidermolysis bullosa released by BioMendics
  • 07 Aug 2025 Phase-II clinical trials in Epidermolysis bullosa in USA (Topical) (NCT07027345)

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