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Enlicitide - Merck Sharp & Dohme

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Drug Profile

Enlicitide - Merck Sharp & Dohme

Alternative Names: Enlicitide Chloride; Enlicitide decanoate; LIPFENDRA; MK-0616

Latest Information Update: 21 Sep 2026

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At a glance

  • Originator Merck Sharp & Dohme Corp.
  • Class Antihyperlipidaemics; Cyclic peptides; Urologics
  • Mechanism of Action PCSK9 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Hypercholesterolaemia; Hyperlipoproteinaemia type IIa
  • Preregistration Dyslipidaemias
  • Phase III Hyperlipidaemia

Most Recent Events

  • 16 Sep 2026 Merck Sharp and Dohme plans phase III MK-0616 trial in Hyperlipidaemia and Hypercholesterolaemia in India in October 2026 (PO) (NCT07821944)
  • 31 Aug 2026 Merck Sharp & Dohme initiates a phase I trial (In volunteers) in USA (PO, Tablet) (NCT07776665)
  • 25 Aug 2026 Merck Sharp & Dohme plans a phase I trial (In volunteers) (PO, Tablet), in August 2026 (NCT07776665)

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