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Enlicitide decanoate - Merck Sharp & Dohme

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Drug Profile

Enlicitide decanoate - Merck Sharp & Dohme

Alternative Names: Enlicitide Chloride; MK-0616

Latest Information Update: 28 Apr 2026

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At a glance

  • Originator Merck Sharp & Dohme Corp.
  • Class Antihyperlipidaemics; Cyclic peptides; Urologics
  • Mechanism of Action PCSK9 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Hypercholesterolaemia; Hyperlipidaemia; Hyperlipoproteinaemia type IIa

Most Recent Events

  • 28 Apr 2026 No recent reports of development identified for phase-I development in Hypercholesterolaemia(In volunteers) in China (PO, Capsule)
  • 31 Mar 2026 Efficacy and adverse event data from the phase III CORALreef AddOn trial in Hypercholesterolaemia released by Merck
  • 16 Mar 2026 Merck Sharp & Dohme plans the phase I MK-0616-041 trial (In volunteers) in March 2026 (PO) (NCT07481708)

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