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Enlicitide decanoate - Merck Sharp & Dohme

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Drug Profile

Enlicitide decanoate - Merck Sharp & Dohme

Alternative Names: Enlicitide Chloride; MK-0616

Latest Information Update: 14 Nov 2025

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At a glance

  • Originator Merck Sharp & Dohme Corp.
  • Class Antihyperlipidaemics; Cyclic peptides; Urologics
  • Mechanism of Action PCSK9 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Hypercholesterolaemia; Hyperlipoproteinaemia type IIa

Most Recent Events

  • 10 Nov 2025 Efficacy and adverse event data from a phase CORALreef HeFH III trial in Hyperlipoproteinaemia type IIa released by Merck Sharp & Dohme Corp
  • 08 Nov 2025 Efficacy data from phase III trial in Hypercholesterolaemia released by Merck
  • 14 Oct 2025 Merck Sharp & Dohme plans a phase III trial for Hypercholesterolaemia (PO), in November 2025 (NCT07216482) (EUCT2025-521495-54-00)

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