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LOXO 435

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Drug Profile

LOXO 435

Alternative Names: LOX-24350; LOXO-435; LY-3866288

Latest Information Update: 11 Dec 2024

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At a glance

  • Originator Loxo Oncology
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Type 3 fibroblast growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours; Urogenital cancer

Most Recent Events

  • 28 Oct 2024 Eli Lilly and Company initiates enrolment in a phase-I trial (In volunteers) in USA (PO) (NCT06644378),
  • 17 Oct 2024 Eli Lilly and Company plans a phase I pharmacokinetics trial (In volunteers) in USA (PO)(NCT06641037)
  • 15 Oct 2024 Eli Lilly and Company plans a phase I trial in volunteers in the USA (NCT06641037)

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