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LOXO 435

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Drug Profile

LOXO 435

Alternative Names: LOX-24350; LOXO-435; LY-3866288

Latest Information Update: 05 Jun 2023

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At a glance

  • Originator Loxo Oncology
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Type 3 fibroblast growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours; Urogenital cancer

Most Recent Events

  • 19 Jan 2023 Phase-I clinical trials in Solid tumours (Late-stage disease, Metastatic disease, Monotherapy) in Japan, Australia (PO) (NCT05614739)
  • 19 Jan 2023 Phase-I clinical trials in Urogenital cancer (Combination therapy, Late-stage disease, Metastatic disease) in Australia, Japan (PO) (NCT05614739)
  • 19 Jan 2023 Phase-I clinical trials in Urogenital cancer (Late-stage disease, Metastatic disease, Monotherapy) in Australia, Australia, Japan (PO) (NCT05614739)

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