Drug Profile

LOXO 435

Alternative Names: LOX-24350; LOXO-435; LY-3866288

Latest Information Update: 07 Feb 2025

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At a glance

Originator Loxo Oncology
Class Antineoplastics; Small molecules
Mechanism of Action Type 3 fibroblast growth factor receptor antagonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Solid tumours; Urogenital cancer

Most Recent Events

03 Jan 2025 Eli Lilly and Company completes phase-I trial (In volunteers) in USA (PO) (NCT06644378),
02 Dec 2024 Eli Lilly and Company completes a phase I pharmacokinetics trial (In volunteers) in USA (PO)(NCT06641037)
28 Oct 2024 Eli Lilly and Company initiates enrolment in a phase-I trial (In volunteers) in USA (PO) (NCT06644378),

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