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PPMX T003

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Drug Profile

PPMX T003

Alternative Names: PPMX-T003

Latest Information Update: 14 Feb 2025

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At a glance

  • Originator Perseus Proteomics
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Transferrin receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Large granular lymphocytic leukaemia
  • Phase I Polycythaemia vera
  • No development reported Haematological malignancies

Most Recent Events

  • 07 Dec 2024 Adverse events, efficacy and pharmacokinetics data from a phase I trial in Polycythaemia vera presented at the 66th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2024)
  • 19 Jul 2023 PPMX T003 is still in trials for Polycythaemia-vera in Japan (NCT05863234)
  • 28 Jun 2023 No recent reports of development identified for phase-I development in Polycythaemia-vera in Japan (IV)

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