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AGEN 1571

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Drug Profile

AGEN 1571

Alternative Names: AGEN-1571

Latest Information Update: 27 Jan 2026

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At a glance

  • Originator Agenus
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Leukocyte immunoglobulin-like receptor B1 antagonists; Natural killer cell stimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 27 Jan 2026 Phase I development for Solid-tumours (Combination therapy, Late-stage disease, Metastatic disease, Monotherapy) is ongoing in the US (IV)
  • 23 Dec 2024 Agenus completes a Phase-I trial in Solid tumours (Late-stage disease, Metastatic disease, Monotherapy, Combination therapy) in USA (NCT05377528)
  • 19 Jul 2022 Phase-I clinical trials in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease) in USA (IV) (NCT05377528)

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