XL 114
Alternative Names: AUR 104; XL-114Latest Information Update: 28 May 2025
At a glance
- Originator Aurigene Discovery Technologies
- Developer Aurigene Oncology
- Class Antineoplastics; Small molecules
- Mechanism of Action MALT1 protein inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Preclinical Solid tumours
- No development reported Non-Hodgkin's lymphoma
Most Recent Events
- 28 May 2025 No recent reports of development identified for phase-I development in Non-Hodgkin's-lymphoma(Second-line therapy or greater) in USA (PO, Tablet)
- 19 Jul 2023 Exelixis terminates a phase I trial in Non-Hodgkin's lymphoma (Second-line therapy or greater) in USA (PO) due to sponsor reasons (NCT05144347)
- 12 Apr 2022 Phase-I clinical trials in Non-Hodgkin's lymphoma (Second-line therapy or greater) in USA (PO) (NCT05144347)