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SynKIR 110

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Drug Profile

SynKIR 110

Alternative Names: Anti-mesothelin killer immunoglobulin-like receptor based chimeric antigen receptor T cell therapy - Verismo Therapeutics; KIR-CAR-meso - Verismo Therapeutics; SynKIR-meso; SynKIR-meso CAR-T cells; SynKIR™-110

Latest Information Update: 25 Aug 2026

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At a glance

  • Originator Verismo Therapeutics
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mesothelioma
  • New Molecular Entity No

Highest Development Phases

  • Phase I Cholangiocarcinoma; Fallopian tube cancer; Mesothelioma; Ovarian cancer; Peritoneal cancer
  • Preclinical Pancreatic cancer; Solid tumours

Most Recent Events

  • 22 Apr 2026 Adverse events and pharmacodynamic data from a first-in-human phase I trial in Solid tumours presented at the 117th Annual Meeting of the American Association for Cancer Research (AACR-2026)
  • 20 Apr 2026 Adverse events and efficacy data from a first-in-human phase I trial in Ovarian cancer, Mesothelioma, and Cholangiocarcinoma released by Verismo Therapeutics
  • 10 Nov 2025 Pharmacodynamics data from a preclinical trial in Solid tumours released by Verismo Therapeutics

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