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AB 5006

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Drug Profile

AB 5006

Alternative Names: AB-5006; AX-5006; VT-5006

Latest Information Update: 01 Dec 2025

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At a glance

  • Originator Axial Biotherapeutics
  • Developer Vertero Therapeutics
  • Class Antiparkinsonians; Small molecules
  • Mechanism of Action Escherichia coli csgA protein aggregation inhibitors; Gastrointestinal microbiome modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Parkinson's disease

Most Recent Events

  • 01 Dec 2025 Vertero Therapeutics plans to initiate a phase II trial for Parkinson's disease (In volunteers) (PO)
  • 24 Nov 2025 Phase-I clinical trials in Parkinson's disease (PO)
  • 29 Mar 2023 Axial Therapeutics plans to file an IND application for Parkinson's disease

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