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ER 100

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Drug Profile

ER 100

Alternative Names: ER-100

Latest Information Update: 03 Feb 2026

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At a glance

  • Originator Harvard University
  • Developer Life Biosciences
  • Class Eye disorder therapies; Gene therapies
  • Mechanism of Action Gene expression modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Preclinical Ischaemic optic neuropathy; Open-angle glaucoma

Most Recent Events

  • 29 Jan 2026 US FDA approves IND application for ER 100 in Non-arteritic anterior ischaemic optic neuropathy (NAION) and open angle glaucoma
  • 22 Jul 2025 Life Biosciences plans clinical trial for ER 100 for glaucoma and non-arteritic anterior ischaemic optic neuropathy in the first quarter of 2026 (NCT07290244)
  • 21 Oct 2024 Pharmacodynamics data from a preclinical trials in Ischaemic optic neuropathy released by Life Biosciences

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