Drug Profile

SPVN 20

Alternative Names: AAV-GIRK2 - SparingVision; SPVN-20

Latest Information Update: 04 Nov 2025

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At a glance

Originator GAMUT Therapeutics
Developer SparingVision
Class Eye disorder therapies; Gene therapies
Mechanism of Action Gene transference; Inwardly rectifying potassium channel modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

Highest Development Phases

Phase I Retinitis pigmentosa

Most Recent Events

28 Oct 2025 Phase-I clinical trials in Retinitis pigmentosa (Late-stage disease) in Belgium (Intravitreous)
28 Oct 2025 Phase-I clinical trials in Retinitis pigmentosa (Late-stage disease) in Ireland, France (Intravitreous)
28 Oct 2025 Regulatory body approves CTA application for SPVN 20 in Retinitis pigmentosa, prior to October 2025

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