Drug Profile

SPVN 20

Alternative Names: AAV-GIRK2 - SparingVision; SPVN-20

Latest Information Update: 25 Aug 2025

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At a glance

Originator GAMUT Therapeutics
Developer SparingVision
Class Eye disorder therapies; Gene therapies
Mechanism of Action Gene transference; Inwardly rectifying potassium channel modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

25 Aug 2025 SparingVision plans a phase I trial for Cone rod dystrophies (Late-stage disease) in Belgium (Intravitreous) (CTIS2025-520665-47-00)
11 Jul 2025 Phase-I clinical trials in Retinitis pigmentosa (Ophthalmic), prior to July 2025 (SparingVision pipeline, July 2025)
13 Oct 2021 Preclinical trials in Retinitis pigmentosa in France (Ophthalmic) before October 2021

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