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KIO 301

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Drug Profile

KIO 301

Alternative Names: B-203; BENAQ; KIO-300; KIO-301

Latest Information Update: 21 Aug 2026

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At a glance

  • Originator Bayon Therapeutics
  • Developer Kiora Pharmaceuticals
  • Class Amides; Aniline compounds; Antiepileptic drugs; Aza compounds; Eye disorder therapies; Small molecules
  • Mechanism of Action Hyperpolarisation activated cation channel antagonists; Voltage-gated potassium channel inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Retinitis pigmentosa; Choroideraemia; Stargardt disease; Usher syndromes
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Choroideraemia; Retinitis pigmentosa; Stargardt disease
  • Preclinical Epilepsy

Most Recent Events

  • 19 Aug 2026 KIO 301 licensed to Chung Kun Dang Pharmaceutical in South Korea
  • 19 Aug 2026 Kiora Pharmaceuticals plans a phase III registrational trial for Retinitis pigmentosa
  • 18 Jun 2026 Preclinical trials in Epilepsy in USA (unspecified route), prior to June 2026

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