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ENTR 601 44

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Drug Profile

ENTR 601 44

Alternative Names: ENTR-601-44; Exon 44 Skipping Oligonucleotide - Entrada Therapeutics

Latest Information Update: 17 Aug 2025

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At a glance

  • Originator Entrada Therapeutics
  • Class Drug conjugates; Oligonucleotides
  • Mechanism of Action Nucleic acid modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Duchenne muscular dystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Duchenne muscular dystrophy

Most Recent Events

  • 30 Jun 2025 Phase-I/II clinical trials in Duchenne muscular dystrophy (In children, In adolescents) in Spain, Belgium (IV) (NCT07037862)
  • 24 Feb 2025 US FDA lifts the clinical hold on ENTR 601 44 to initiate phase Ib ELEVATE-44-102 trial for Duchenne muscular dystrophy in the US
  • 24 Feb 2025 Entrada Therapeutics plans a phase Ib ELEVATE-44-102 trial for Duchenne muscular dystrophy in the US in the first half of 2026

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