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ENTR 601 44

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Drug Profile

ENTR 601 44

Alternative Names: ENTR-601-44; Exon 44 Skipping Oligonucleotide - Entrada Therapeutics

Latest Information Update: 24 May 2026

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At a glance

  • Originator Entrada Therapeutics
  • Class Drug conjugates; Oligonucleotides
  • Mechanism of Action Nucleic acid modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Duchenne muscular dystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Duchenne muscular dystrophy

Most Recent Events

  • 07 May 2026 Entrada Therapeutics plans to re-engage with the US FDA to discuss increasing the planned doses in ELEVATE-44-102 study
  • 07 May 2026 Efficacy, adverse events, pharmacokinetics, pharmacodynamics data from the phase I/II ELEVATE-44-201 trial in Duchenne muscular dystrophy released by Entrada Therapeutics
  • 09 Jan 2026 ENTR 601 44 receives Rare Pediatric Disease Designation for Duchenne muscular dystrophy in USA

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