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SGNPDL 1V

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Drug Profile

SGNPDL 1V

Alternative Names: PDL1V; PF-08046054; SGN-PDL1V

Latest Information Update: 16 Jun 2025

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At a glance

  • Originator Seagen
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Cell death stimulants; Mitosis inhibitors; Programmed cell death-1 ligand-1 inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 25 Apr 2025 Pharmacodynamics data from a preclinical study in Solid tumours presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 20 Mar 2025 SGNPDL 1V is still in phase I trial for Solid tumours (Monotherapy, Late-stage disease, Second-line therapy or greater, Inoperable/Unresectable, Metastatic disease) in USA (IV) (Pfizer pipeline, March 2025)
  • 28 Feb 2025 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA (IV, Injection)

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