Felmetatug vedotin - Pfizer
Alternative Names: PF-08046048; SGN-B7H4VLatest Information Update: 15 Dec 2023
At a glance
- Originator Seagen
- Class Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; Mitosis inhibitors; Tubulin polymerisation inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Solid tumours
Most Recent Events
- 14 Dec 2023 Seagen has been acquired by Pfizer
- 20 Oct 2023 Adverse events data from a phase I trial in Solid tumour presented at the 48th European Society for Medical Oncology Congress (ESMO-2023)
- 08 Apr 2022 Pharmacodynamics data from a preclinical trial in Solid tumours presented at the 113th Annual Meeting of the American Association for Cancer Research (AACR-2022)