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A2B 694

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Drug Profile

A2B 694

Alternative Names: A2B-694

Latest Information Update: 09 Sep 2025

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At a glance

  • Originator A2 Biotherapeutics
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 09 Sep 2025 Adverse events and pharmacodynamic data from the phase I/II trial in Solid tumours presented at the 61st Annual Meeting of the American Society of Clinical Oncology (ASCO-2025)
  • 31 Jan 2024 Phase-I/II clinical trials in Solid tumours (Recurrent, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT06051695)
  • 28 Sep 2023 A2 Biotherapeutics plans a phase I/II trial for Solid tumors (Recurrent, Inoperable/Unresectable, Metastatic disease, Late-stage disease, Second-line therapy or greater) in USA (IV) in Q1 2024, (NCT06051695)

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