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GENV HEM

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Drug Profile

GENV HEM

Alternative Names: AAV8.FVa; GENV-HEM

Latest Information Update: 28 Dec 2025

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At a glance

  • Originator University of North Carolina
  • Developer GeneVentiv Therapeutics
  • Class Antihaemorrhagics; Gene therapies
  • Mechanism of Action Factor V replacements; Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Haemophilia
  • New Molecular Entity No

Highest Development Phases

  • No development reported Haemophilia

Most Recent Events

  • 28 Dec 2025 No recent reports of development identified for preclinical development in Haemophilia in USA (Parenteral, Infusion)
  • 29 Oct 2025 GeneVentiv Therapeutics announces intention to submit IND application to regulatory body for Haemophilia in 2026
  • 16 Apr 2024 GeneVentiv Therapeutics receives SBIR grant from the National Heart Lung Blood Institute (NHLBI) for GENV-HEM development in Haemophilia

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