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CFT 1946

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Drug Profile

CFT 1946

Alternative Names: CFT-1946

Latest Information Update: 20 Sep 2024

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At a glance

  • Originator C4 Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proto-oncogene protein b-raf degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Malignant melanoma; Solid tumours

Most Recent Events

  • 13 Sep 2024 Efficacy, adverse event and pharmacokinetics data from phase I/II trial in Solid tumours released by C4 Therapeutics
  • 18 Jul 2024 Phase-I/II clinical trials in Malignant melanoma (Late-stage disease, Metastatic disease, Combination therapy, Second-line therapy or greater) in USA, Spain, France (PO) (NCT05668585)
  • 18 Jul 2024 Phase-I/II clinical trials in Malignant melanoma (Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA, France, Spain (PO) (NCT05668585)

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