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Selnoflast - Roche

Drug Profile

Selnoflast - Roche

Alternative Names: NLRP3i - Roche; RG 6418; RO-7486967; Somalix

Latest Information Update: 13 May 2024

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At a glance

  • Originator Inflazome
  • Developer Roche
  • Class Anti-inflammatories; Antiasthmatics; Antiparkinsonians; Aromatic hydrocarbons; Piperidines; Small molecules; Urea compounds
  • Mechanism of Action NLRP3 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Asthma; Chronic obstructive pulmonary disease; Inflammation; Parkinson's disease; Ulcerative colitis

Most Recent Events

  • 09 May 2024 Phase I development for Inflammation is ongoing in Ireland (Roche pipeline, May 2024)
  • 10 Jul 2023 Phase-I clinical trials in Asthma in Netherlands, Germany, United Kingdom, Canada, Belgium (PO) (ISRCTN73873157)
  • 28 Jun 2023 No recent reports of development identified for phase-I development in Inflammation in Ireland (PO)
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