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TYRA 300

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Drug Profile

TYRA 300

Alternative Names: TYRA-300; TYRA-300-B01

Latest Information Update: 15 Jun 2025

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At a glance

  • Originator Tyra Biosciences
  • Class Antineoplastics; Chlorinated hydrocarbons; Ethers; Indazoles; Pyridines; Small molecules; Spiro compounds; Sulfones
  • Mechanism of Action Type 3 fibroblast growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Achondroplasia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Achondroplasia; Bladder cancer
  • Phase I/II Solid tumours
  • Preclinical Hypochondroplasia

Most Recent Events

  • 05 Jun 2025 Phase-II clinical trials in Bladder cancer in USA (PO) (NCT06995677)
  • 07 Mar 2025 Phase-II clinical trials in Achondroplasia (In children) in USA (PO) (NCT06842355)
  • 10 Jan 2025 Tyra Biosciences plans a phase-II SURF302 trial for Bladder cancer in USA (PO) in the first half of 2025

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