LCAR AIO
Alternative Names: LCAR-AIO; VHH CAR-TLatest Information Update: 25 Jun 2025
At a glance
- Originator Legend Biotech USA
- Developer Legend Biotech USA; Nanjing Legend Biotech
- Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I Autoimmune disorders
- Preclinical Diffuse large B cell lymphoma; Non-Hodgkin's lymphoma
- No development reported B-cell lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma
Most Recent Events
- 17 Jun 2025 Phase-I clinical trials in Autoimmune disorders (Second-line therapy or greater) in China (Parenteral) (NCT06869278)
- 28 Apr 2025 No recent reports of development identified for phase-I development in B-cell lymphoma(In the elderly, Second-line therapy or greater, In adults) in China (Parenteral)
- 28 Apr 2025 No recent reports of development identified for phase-I development in Precursor-B-cell-lymphoblastic-leukaemia-lymphoma(In the elderly, Second-line therapy or greater, In adults) in China (Parenteral)