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LCARAIO

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Drug Profile

LCARAIO

Alternative Names: LCAR-AIO; VHH CAR-T

Latest Information Update: 25 Oct 2024

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At a glance

  • Originator Legend Biotech USA
  • Developer Legend Biotech USA; Nanjing Legend Biotech
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I B-cell lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma
  • Preclinical Diffuse large B cell lymphoma; Non-Hodgkin's lymphoma

Most Recent Events

  • 20 Oct 2024 Legend Biotech in collaboration with Wuhan Union Hospital plans a early phase I trial for Systemic lupus erythematosus in China (Parentral) in October 2024(NCT06653556)
  • 28 Mar 2022 Nanjing Legend Biotech plans a phase I trial for Precursor cell lymphoblastic leukaemia lymphoma (Second-line therapy or greater, In adults, In the elderly) in China, in April 2022 (NCT05292898)
  • 14 Mar 2022 Phase-I clinical trials in Precursor B-cell lymphoblastic leukaemia-lymphoma (Second-line therapy or greater, In adults, In the elderly) in China (Parenteral) (NCT05292898)

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