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TSC 204

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Drug Profile

TSC 204

Alternative Names: TSC-204; TSC-204-A0201; TSC-204-C07; TSC-204-C0702

Latest Information Update: 16 Dec 2025

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At a glance

  • Originator TScan Therapeutics
  • Class Antineoplastics; Gene therapies; Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Anal cancer; Cervical cancer; Head and neck cancer; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer

Most Recent Events

  • 12 Nov 2025 TScan Therapeutics paused enrollment a phase I PLEXI-T trial in Solid tumours in the US due to focus on preclinical development of in vivo engineering to treat patients with solid tumors (NCT05973487)
  • 06 Mar 2024 Tscan Therapeutics plans a phase I trial for Solid tumours in the first quarter of 2024
  • 06 Mar 2024 US FDA approves IND application for TSC 204 for TSC-204-A0101 in Solid tumours

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