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Tolododekin alfa - Ankyra Therapeutics

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Drug Profile

Tolododekin alfa - Ankyra Therapeutics

Alternative Names: ANK-101

Latest Information Update: 09 Dec 2025

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At a glance

  • Originator Ankyra Therapeutics
  • Class Antineoplastics; Cytokines; Drug conjugates; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Interleukin 12 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 22 Oct 2025 Phase-I clinical trials in Non-small cell lung cancer (Combination therapy, Metastatic disease, Late-stage disease, First-line therapy) in USA (Intratumoural) (NCT07027514)
  • 22 Oct 2025 Phase-I clinical trials in Non-small cell lung cancer (Combination therapy, Second-line therapy or greater, Late-stage disease, Metastatic disease) in USA (Intratumoural) (NCT07027514)
  • 06 Aug 2025 Ankyra Therapeutics plans a phase I trial in Squamous cell cancer (In adolescents, In adults, In the elderly, Metastatic disease, Second-line therapy or greater) (Intratumoural) (NCT07100925)

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