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FX 345

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Drug Profile

FX 345

Alternative Names: FX-345

Latest Information Update: 11 Jan 2024

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At a glance

  • Originator Frequency Therapeutics
  • Developer Korro Bio
  • Class Small molecules
  • Mechanism of Action Glycogen synthase kinase 3 inhibitors; Stem cell stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Sensorineural hearing loss

Most Recent Events

  • 13 Feb 2023 Discontinued - Phase-I for Sensorineural hearing loss in USA (Intratympanic) due to discouraging clinical trial results
  • 15 Dec 2022 Phase-I clinical trials in Sensorineural hearing loss in USA (Intratympanic) (NCT05664100)
  • 09 Aug 2022 Frequency Therapeutics plans a phase Ib trial for Sensorineural hearing loss in the fourth quarter of 2022

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